A F/21 with active drug abuse was admitted for generalized tonic-clonic convulsion. She had history of bilateral loin pain for which she underwent non-contrast CT abdomen and pelvis. Which drug of abuse can cause such CT changes?
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A. Heroin
B. LSD
C. Ketamine
D. Benzodiazepines
Answer: C
The above non-contrast CT films showed bilateral hydronephrosis and hydroureter. No stone was seen, bladder was not distended and its wall was thickened. RFT was normal. Subsequent urological investigation showed bladder dysfunction, related to ketamine abuse.
Ketamine has become a very common drug of abuse in Hong Kong. Similar cases have been described in local journals and at our website.
References
1. Peggy SK Chu, SC Kwok, KM Lam, TY Chu, Steve WH Chan, CW Man, WK Ma, KL Chui, MK Yiu, YC Chan, ML Tse, FL Lau. ‘Street ketamine’–associated bladder dysfunction: a report of ten cases. August, 2007 (free full-text at HKMJ website here)
2. M/26 with Acute Renal Failure
3. REUTERS