Dr Siu Kin Lok, ICU, North District Hospital, Hong Kong
Objective
To identify the risk factors associated with the development of Methicillin resistant Staphylococcus aureus (MRSA) infections among the MRSA colonizer in a local population of intensive care unit (ICU) patients.
Design
Retrospective cohort study
Setting
An adult intensive care unit of a 12-14 beds regional hospital.
Patients
The subjects of the study were patients with positive MRSA screening of the PCR test upon admission to ICU from January 2008 to May 2011. Data were collected from the hospital electronic information system and the medical files.
Results
Between January 2008 and May 2011, a total of 126 patients with positive PCR for MRSA upon ICU admission were included in the study. There were total 23 patients with documented MRSA infections among them. In univariate analysis, accommodation in institution, a history of hypertension, use of antimicrobials in the past 3 months, sepsis upon admission, operation done during current admission, use of quinolone, positive MRSA of the pooled swab for screening upon discharge and the hospital length of stay were found statistically significant.
Conclusion
The study demonstrated a number of risk factors associated with MRSA infections among the MRSA colonizers in a local intensive care population.
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