Hugh Pennington a. The Lancet Infectious Diseases, Early Online Publication, 23 June 2011
In The Lancet Infectious Diseases , Helge Karch and colleagues 1 characterise the virulence profiles of E coli O104:H4 isolates from 80 patients in the large outbreak in Germany.
The researchers show that all the isolates belong to a clone (HUSEC041) first isolated in Germany from a patient with haemolytic uraemic syndrome in 2001. The members of this clone have virulence profiles that combine those of two different enterovirulent E coli —enterohaemorrhagic E coli and enteroaggregative E coli . They have th …
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