Peter Nagele a. The Lancet, Early Online Publication, 19 January 2011doi:10.1016/S0140-6736(10)62309-4
Out-of-hospital cardiac arrest remains a grim situation. Without cardiopulmonary resuscitation (CPR), cardiac arrest is invariably fatal, and even under the best possible circumstances survival rates often do not exceed 10%.
Resuscitation researchers have investigated many strategies and methods to increase survival and improve neurological recovery after out-of-hospital cardiac arrest. Many have failed and only a few clearly improve outcomes, such as therapeutic hypothermia or public-access defibrillation.1, 2
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