N Engl J Med 2011; 364:185-188. January 13, 2011
The midazolam dose of 0.15 mg per kilogram of body weight per hour described in the article by Holzer (Sept. 23 issue)1 and in other articles on therapeutic hypothermia2 is very similar to the recommended dose of midazolam used to adapt critically ill patients without neurologic problems to mechanical ventilation.3
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