Robert A Fowler a, Philippe Jouvet b. The Lancet, Early Online Publication, 27 October 2010
In The Lancet Nabihah Sachedina and Liam Donaldson1 analyse paediatric mortality related to pandemic influenza A H1N1 in England. The investigators used sensitive case-finding procedures and follow-up ascertainment of H1N1 status to determine population mortality rates for children of different ages and at various pre-existing states of health.
Case-fatality rates in children with H1N1 infection are difficult to derive and are probably underestimated.2 Furthermore, because some H1N1-related deaths will have inevitably been missed, it is almost certain that the 70 deaths reported in this study are a conservative estimate. Nevertheless, the mortality rates are similar to those in other reports, and the true value of this study is the comparison of mortality in various groups of children.
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