2010 Mar 4 – NEJM Editorial: Treating Shock — Old Drugs, New Ideas

Jerrold H. Levy, M.D. NEJM Volume 362:841-843 March 4, 2010 Number 9
Circulatory shock is a medical emergency that is characterized by hypotension and decreased tissue perfusion; if left untreated, it can lead to irreversible cellular injury and death.


Hypotension associated with shock can be the result of any of a number of factors, depending on the type of shock; these include biventricular dysfunction, intravascular hypovolemia, and the vascular effects of inflammatory responses.

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