2010 Jan 27 – JAMA Editorial: Should Glucocorticoid-Induced Hyperglycemia Be Treated in Patients With Septic Shock?

Greet Van den Berghe, MD, PhD. JAMA. 2010;303(4):365-366.
Critical illness, in particular severe sepsis, induces insulin resistance and hyperglycemia. Corticosteroids are often used for reversal of fluid- and vasopressor-resistant septic shock. Such an adjuvant treatment aggravates illness-induced hyperglycemia, even in a low-dose steroid regimen.1


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