Arthur P. Wheeler, MD, FCCP and Todd W. Rice, MD, MSc. CHEST January 2010 vol. 137 no. 1 185-194
This manuscript provides an overview of how to interpret in vitro clotting studies and how to select studies to evaluate patients with bleeding disorders in the ICU.
It provides a practical approach to understanding the complex subject of clotting factor abnormalities, including the most common problems of preanalytical error and anticoagulation therapy. Limitations and pitfalls of diagnostic testing are highlighted.
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