LL Chang, OY Tam, AMC Kwan, HP Shum, KC Chan, WW Yan; ASAIOJ 8 May 2014 [Epub ahead of print]
Patients on extracorporeal membrane oxygenation (ECMO) are critically ill and fluid balance need to be managed as accurately as possible. Previous studies have focused on insensible water loss through neonatal ECMO circuit and showed that water loss through the ECMO circuit was correlated with the sweep gas flow rates. Current study is the first study focusing on insensible water loss through adult ECMO circuit.
An in vitro extracorporeal circuit consisting of Jostra Quadrox D membrane oxygenator and centrifugal pump was primed with normal saline. The amount of water loss through the ECMO circuit was found to be linearly correlated with the sweep gas flow rate and fluid temperature. For every liter per minute of sweep gas flow at 37[degrees]C, 0.046ml/min of water will be lost; and for every change of fluid temperature by 1[degrees]C, water content loss will be changed by 0.0026ml/min by multiple linear regression (R2=0.996). The average daily water loss for every liter per minute of sweep gas flow at 33C, 34C,35C,36C,37C,38C and 39C were 51.3ml/day, 55ml/day, 58.8ml/day, 62.5ml/day, 66.2ml/day, 70.0ml/day and 73.7ml/day respectively.
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