2012.04.11 Quiz: Anidulafungin, Caspofungin and Micafungin

Which of the folowing about anidulafungin (A), Caspofungin (C) and Micafungin (M) is incorrect?
A. All three can treat candidemia
B. C required dose adjustments for moderate hepatic impairment
C. All are highly protein bound
D. M is the only one which requires a loading dose
E. A may cause histamine-mediated symptoms, but infrequent if infusion rate is low