2010.11.28 Quiz: Remote Ischemic Preconditioning (RIPC)

Which of the following is not correct about Ischemic Preconditioning (RIPC)?
A. It is the phenomenon in which transient non-lethal ischemica and reperfusion of one organ or tissue confers resistance to a subsequent episode of lethal ischemia reperfusion injury in a remote organ or tissue.
B. One example is: intermittent arm ischemia through 4 cycles of 5-min inflation and 5-min deflation of a blood pressure cuff may increase myocardia salvage in patients with suspected acute myocardial infarction undergoing primary coronary intervention.
C. Such inter-organ protection is not limited to between upper limb and heart.
D. Potential mechanisms and mediators include neural, humoral and a systemic response.
E. If the ischemia in the preconditioning stage is not discontinued intermittently, the protective effect to another organ is even better.