Which of the following is incorrect?
A. The first recognized case of human disease from a swine influenza triple reassortant influenza A (H1N1) virus occurred in a 17-year-old who had been exposed to pigs at a slaughterhouse in Wisconsin.
B. In April 2009, in the first two cases of S-OIV were identified in the United States, genetic analysis of the strains showed that they were derived from a new reassortment of six gene segments from the known triple reassortant swine virus, and two gene segments (NA and matrix protein) from the Eurasian influenza A (H1N1) swine virus lineage.
C. The 2009 lineage carries three gene segments that share a common (albeit remote) descent from the 1918 virus with the human seasonal virus.
D. It has been found that cytotoxic T lymphocytes that are generated by seasonal influenza viruses against conserved epitopes could not provide heterotypic immune responses that could dampen transmission of the novel H1N1 virus.
Answer: D
Cytotoxic T lymphocytes that are generated by seasonal influenza viruses against conserved epitopes might provide heterotypic immune responses that could dampen transmission, even in the absence of measurable antibody protection.
Reference
David M. Morens, M.D., Jeffery K. Taubenberger, M.D., Ph.D., and Anthony S. Fauci, M.D. Volume 361:225-229 July 16, 2009 Number 3. Perspective: The Persistent Legacy of the 1918 Influenza Virus. NEJM. Volume 361:225-229 July 16, 2009 Number 3