Kilgannon JH, Roberts BW, Jones AE, Mittal N, Cohen E, Mitchell J, Chansky ME, Trzeciak S.; Crit Care Med. 2014 Sep;42(9):2083-91.
Objectives: Guidelines for post–cardiac arrest care recommend blood pressure optimization as one component of neuroprotection. Although some retrospective clinical studies suggest that postresuscitation hypotension may be harmful, and laboratory studies suggest that a postresuscitation hypertensive surge may be protective, empirical data are few. In this study, we prospectively measured blood pressure over time during the postresuscitation period and tested its association with neurologic outcome.
2014 Sep - Lactate Clearance Is a Useful Biomarker for the Prediction of All-Cause Mortality in Critically Ill Patients: A Systematic Review and Meta-Analysis
Zhang Z, Xu X.; Crit Care Med. 2014 Sep;42(9):2118-25.
Objectives: Lactate clearance has been widely investigated for its prognostic value in critically ill patients. However, the results are conflicting. The present study aimed to explore the diagnostic accuracy of lactate clearance in predicting mortality in critically or acutely ill patients.
2014 Sep - Intra-Aortic Balloon Pump Effects on Macrocirculation and Microcirculation in Cardiogenic Shock Patients Supported by Venoarterial Extracorporeal Membrane Oxygenation
Petroni T, Harrois A, Amour J, Lebreton G, Brechot N, Tanaka S, Luyt CE, Trouillet JL, Chastre J, Leprince P, Duranteau J, Combes A.; Crit Care Med. 2014 Sep;42(9):2075-82.
Objectives: This study was designed to assess the effects on macrocirculation and microcirculation of adding an intra-aortic balloon pump to peripheral venoarterial extracorporeal membrane oxygenation in patients with severe cardiogenic shock and little/no residual left ventricular ejection.
The Hong Kong Society of Critical Care Medicine (香港危重病學會)will be holding its Annual Scientific Meeting (ASM) 2014(週年學術會議2014)on 30 November, 2014 (Sunday) at the Intercontinental Grand Stanford Hong Kong. And it is our pleasure to have the meeting supported by the Hong Kong Association of Critical Care Nurses (香港危重病學護士協會).
This is a major event for all Hong Kong doctors, nurses and allied health professionals working with critically ill patients. Similar to previous years, we will have renowned overseas and local speakers to enlighten us on important ICU topics in plenary lectures & seminars.
Continuing our tradition, SimWARS will be held and teams of doctors & nurses are invited to join this exciting competition. Young specialists and critical care nurses are encouraged to submit abstracts of original research papers for free-paper presentation, and share with the audience about their studies.
Details of the programme will be released soon. We sincerely hope to make the ASM an enjoyable and interesting event for all of you.
Looking forward to seeing you.
Dr. SIN, Kai Cheuk
Chairman of the Organizing Committee for HKSCCM ASM 2014
Date: 4 Sep 2014
David E. Leaf, Anas Raed, Michael W. Donnino, Adit A. Ginde, and Sushrut S. Waikar Am. J. Resp. Crit. Care Med. Sep 1, 2014, vol. 190, no. 5: 533-541
Rationale: Vitamin D and its metabolites have potent immunomodulatory effects in vitro, including up-regulation of cathelicidin, a critical antimicrobial protein.
2014 Sep 1 - A Novel Tumor Necrosis Factor–mediated Mechanism of Direct Epithelial Sodium Channel Activation
István Czikora, Abdel Alli, Hui-Fang Bao, David Kaftan, Supriya Sridhar, Hans-Jürgen Apell, Boris Gorshkov, Richard White, Astrid Zimmermann, Albrecht Wendel, Meike Pauly-Evers, Jürg Hamacher, Irène Garcia-Gabay, Bernhard Fischer, Alexander Verin, Zsolt Bagi, Jean Francois Pittet, Waheed Shabbir, Rosa Lemmens-Gruber, Trinad Chakraborty, Ahmed Lazrak, Michael A. Matthay, Douglas C. Eaton, and Rudolf Lucas Am. J. Resp. Crit. Care Med. Sep 1, 2014, vol. 190, no. 5: 522-532
Rationale: Alveolar liquid clearance is regulated by Na+ uptake through the apically expressed epithelial sodium channel (ENaC) and basolaterally localized Na+-K+-ATPase in type II alveolar epithelial cells. Dysfunction of these Na+ transporters during pulmonary inflammation can contribute to pulmonary edema.
2014 Sep - Characteristics and Outcomes of Patients With Lung Transplantation Requiring Admission to the Medical ICU
Amit Banga, MD, FCCP; Debasis Sahoo, MD; Charles R. Lane, MD; Atul C. Mehta, MD, FCCP; Olufemi Akindipe, MD; Marie M. Budev, DO, MPH, FCCP; Xiao-Feng Wang, PhD; Madhu Sasidhar, MD, FCCP CHEST Sep 2014; 146(3): 590-599
BACKGROUND: There are few data on characteristics and outcomes among patients with lung transplantation (LT) requiring admission to the medical ICU (MICU) beyond the perioperative period.
Date: 22 Sep 2014; Time: 6:30-10pm; Venue: Pearl Ballroom, 2/F, Eaton Hotel, Jordan, Kowloon
2014 Sep - Impact of Early Mobilization on Glycemic Control and ICU-Acquired Weakness in Critically Ill Patients Who Are Mechanically Ventilated
Bhakti K. Patel, MD; Anne S. Pohlman, MSN; Jesse B. Hall, MD, FCCP; John P. Kress, MD, FCCP CHEST Sep 2014; 146(3): 583-589
BACKGROUND: ICU-acquired weakness (ICU-AW) has immediate and long-term consequences for critically ill patients. Strategies for the prevention of weakness include modification of known risk factors, such as hyperglycemia and immobility. Intensive insulin therapy (IIT) has been proposed to prevent critical illness polyneuropathy. However, the effect of insulin and early mobilization on clinically apparent weakness is not well known.
Caroline M. Quill, MD; Sarah J. Ratcliffe, PhD; Michael O. Harhay, MPH; Scott D. Halpern, MD, PhD CHEST Sep 2014; 146(3): 573-582
BACKGROUND: The magnitude and implication of variation in end-of-life decision-making among ICUs in the United States is unknown.
Date: 4 Oct 2014; Time: 14:00 - 18:30; Venue: High Function Room, 1/F, Hong Kong Productivity Council, 78 Tat Chee Avenue, Kowloon Tong, Kowloon
Date: 23/9/2014; Time: 6:30-8:30pm; Venue: Lecture Theatre, G/F, M block, QEH
2014 Sep - A Multicenter, Randomized Clinical Trial of IV Iron Supplementation for Anemia of Traumatic Critical Illness
Pieracci FM, Stovall RT, Jaouen B, Rodil M, Cappa A, Burlew CC, Holena DN, Maier R, Berry S, Jurkovich J, Moore EE.; Crit Care Med. 2014 Sep;42(9):2048-57.
Objective: To evaluate the efficacy of IV iron supplementation of anemic, critically ill trauma patients.
Date: 25 Sept 2014; Time: 18:00-19:30; Venue: Lecture Theatre, 7/F, Block H, PMH
2014 Sep - Relationship Between ICU Bed Availability, ICU Readmission, and Cardiac Arrest in the General Wards
Town JA, Churpek MM, Yuen TC, Huber MT, Kress JP, Edelson DP.; Crit Care Med. 2014 Sep;42(9):2037-41.
Objective: The decision to admit a patient to the ICU is complex, reflecting patient factors and available resources. Previous work has shown that ICU census does not impact mortality of patients admitted to the ICU. However, the effect of ICU bed availability on patients outside the ICU is unknown. We sought to determine the association between ICU bed availability, ICU readmissions, and ward cardiac arrests.
Salvatierra G, Bindler RC, Corbett C, Roll J, Daratha KB.; Crit Care Med. 2014 Sep;42(9):2001-6.
Objective: To determine the relationship between implementation of rapid response teams and improved mortality rate using a large, uniform dataset from one state in the United States.
2014 Sep - Sepsis Severity Score: An Internationally Derived Scoring System From the Surviving Sepsis Campaign Database
Osborn TM, Phillips G, Lemeshow S, Townsend S, Schorr CA, Levy MM, Dellinger RP.; Crit Care Med. 2014 Sep;42(9):1969-76.
Objective: As the Surviving Sepsis Campaign was assessing patient-level data over multiple countries, we sought to evaluate the use of a pragmatic and parsimonious severity-of-illness scoring system for patients with sepsis in an attempt to provide appropriate comparisons with practical application.
Yeung MC, Tong SY, Tong PY, Cheung BH, Ng JY, Leung GK.; Hong Kong Med J. 2014 Aug 1. doi: 10.12809/hkmj134147. [Epub ahead of print]
Objectives: To review the current evidence for the use of viscoelastic haemostatic assays in different surgical settings including trauma, cardiac surgery, liver transplantation, as well as the monitoring of antiplatelet agents and anticoagulants prior to surgery.
2014 Aug - Treatment outcomes of patients with multidrug- and extensive drug-resistant tuberculosis according to drug susceptibility testing to first- and second-line drugs: an individual patient data meta-analysis
Bastos ML, Hussain H, Weyer K, Garcia-Garcia L, Leimane V, Leung CC, Narita M, Penã JM, Ponce-de-Leon A, Seung KJ, Shean K, Sifuentes-Osornio J, Van der Walt M, Van der Werf TS, Yew WW, Menzies D; on behalf of The Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB; on behalf of The Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB.; Clin Infect Dis. 2014 Aug 5. pii: ciu619. [Epub ahead of print]
BACKGROUND: Individualized treatment for multi-drug resistant tuberculosis (MDR-TB) and extensively drug-resistant (XDR) TB depends upon reliable and valid drug susceptibility tests (DST) for pyrazinamide, ethambutol and second-line TB drugs. However the reliability of these tests is uncertain, due to unresolved methodological issues. We estimated the association of DST results for pyrazinamide, ethambutol, and second line drugs with treatment outcomes in patients with MDR-TB and XDR-TB.
Date: 27 Aug 2014; Venue: HA TFCM Meeting; Speaker: Dr KY Lai (COS, ICU, QEH)