Date: 25/9/2014; Time: 11:00am - 12:30pm; Venue: Lecture Room 3, 1/F, HKEC Training Center, PYNEH
2014 Sep - Sodium bicarbonate in the prevention of cardiac surgery-associated acute kidney injury: a systematic review and meta-analysis
Tie HT, Luo MZ, Luo MJ, Zhang M, Wu QC, Wan JY.; Crit Care. 2014 Sep 12;18(5):517. [Epub ahead of print]
Introduction: Sodium bicarbonate (SBIC) was reported to be a promising approach to prevent cardiac surgery-associated acute kidney injury (CSA-AKI). However, the results remain controversial. We conducted a systematic review and meta-analysis to evaluate the efficacy and safety of SBIC on the prevention of CSA-AKI in adult patients undergoing cardiac surgery.
2014 Sep - In-hospital mortality following treatment with red blood cell transfusion or inotropic therapy during early goal-directed therapy for septic shock: a retrospective propensity-adjusted analysis
Mark DG, Morehouse JW, Hung YY, Kene MV, Elms AR, Liu V, Ballard DW, Vinson DR.; Crit Care. 2014 Sep 12;18(5):496. [Epub ahead of print]
Introduction: We sought to investigate whether treatment of subnormal (<70%) central venous oxygen saturation (ScvO2) with inotropes or red blood cell (RBC) transfusion during early goal-directed therapy (EGDT) for septic shock is independently associated with in-hospital mortality.
Mercedes Garcia-Alvarez, Paul Marik, Rinaldo Bellomo Critical Care 2014, 18:503 (9 September 2014)
There is overwhelming evidence that sepsis and septic shock are associated with hyperlactatemia (sepsis-associated hyperlactatemia (SAHL)). SAHL is a strong independent predictor of mortality and its presence and progression are widely appreciated by clinicians to define a very high-risk population. Until recently, the dominant paradigm has been that SAHL is a marker of tissue hypoxia...
Date: 23 Oct 2014; Venue: Ballroom 1&2, The Mira Hong Kong, Kowloon
Date: 15-20 May 2015; Venue: Colorado Convention Center, 700 14th St, Denver
The American Thoracic Society’s International Conference features the latest scientific and medical advances in pulmonary, critical care, and sleep medicine. With more than 400 sessions, 800 speakers and, 5,700 research abstracts and case studies in 2014, the conference is recognized as the leader in the field. Learn more at: http://conference.thoracic.org/2015/
Date: 25 Sept 2014; Time: 18:00-19:30; Venue: Lecture Theatre, 7/F, Block H, PMH
2014 Aug - High-Protein Enteral Nutrition Enriched With Immune-Modulating Nutrients vs Standard High-Protein Enteral Nutrition and Nosocomial Infections in the ICU
van Zanten AR, Sztark F, Kaisers UX, Zielmann S, Felbinger TW, Sablotzki AR, De Waele JJ, Timsit JF, Honing ML, Keh D, Vincent JL, Zazzo JF, Fijn HB, Petit L, Preiser JC, van Horssen PJ, Hofman Z. ;JAMA. 2014 Aug 6;312(5):514-24.
IMPORTANCE: Enteral administration of immune-modulating nutrients (eg, glutamine, omega-3 fatty acids, selenium, and antioxidants) has been suggested to reduce infections and improve recovery from critical illness. However, controversy exists on the use of immune-modulating enteral nutrition, reflected by lack of consensus in guidelines.
2014 Jul - Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain InjuryA Randomized Clinical Trial
Robertson CS, Hannay HJ, Yamal JM, Gopinath S, Goodman JC, Tilley BC; Epo Severe TBI Trial Investigators, Baldwin A, Rivera Lara L, Saucedo-Crespo H, Ahmed O, Sadasivan S, Ponce L, Cruz-Navarro J, Shahin H, Aisiku IP, Doshi P, Valadka A, Neipert L, Waguspack JM, Rubin ML, Benoit JS, Swank P.; JAMA. 2014 Jul 2;312(1):36-47.
IMPORTANCE: There is limited information about the effect of erythropoietin or a high hemoglobin transfusion threshold after a traumatic brain injury.
OBJECTIVE: To compare the effects of erythropoietin and 2 hemoglobin transfusion thresholds (7 and 10 g/dL) on neurological recovery after traumatic brain injury.
Rello J, Lisboa T, Koulenti D.; Lancet Respir Med. 2014 Sep;2(9):764-774.
Lower respiratory tract infections in mechanically ventilated patients are a frequent cause of antibiotic treatment in intensive-care units. These infections present as severe sepsis or septic shock with respiratory dysfunction in intubated patients. Purulent respiratory secretions are needed for diagnosis, but distinguishing between pneumonia and tracheobronchitis is not easy...
2014 Sep - Hydrocortisone and fludrocortisone for prevention of hospital-acquired pneumonia in patients with severe traumatic brain injury (Corti-TC): a double-blind, multicentre phase 3, randomised placebo-controlled trial
Asehnoune K, Seguin P, Allary J, Feuillet F, Lasocki S, Cook F, Floch H, Chabanne R, Geeraerts T, Roger C, Perrigault PF, Hanouz JL, Lukaszewicz AC, Biais M, Boucheix P, Dahyot-Fizelier C, Capdevila X, Mahe PJ, Maguet PL, Paugam-Burtz C, Gergaud S, Plaud B, Constantin JM, Malledant Y, Flet L, Sebille V, Roquilly A; Corti-TC Study Group.; Lancet Respir Med. 2014 Sep;2(9):706-16
BACKGROUND: Hospital-acquired pneumonia is common after traumatic brain injury, and might be partly a result of traumatic brain injury-induced adrenal insufficiency. We tested the efficacy of low-dose hydrocortisone with fludrocortisone for the prevention of hospital-acquired pneumonia.
Wong EH, Porter JD, Edwards MR, Johnston SL.; Lancet Respir Med. 2014 Aug;2(8):657-670.
Macrolides, such as clarithromycin and azithromycin, possess antimicrobial, immunomodulatory, and potential antiviral properties. They represent a potential therapeutic option for asthma, a chronic inflammatory disorder characterised by airway hyper-responsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness, and coughing. Results from clinical trials, however, have been contentious...
2014 Aug - Point-of-care ultrasonography in patients admitted with respiratory symptoms: a single-blind, randomised controlled trial
Laursen CB, Sloth E, Lassen AT, Christensen Rd, Lambrechtsen J, Madsen PH, Henriksen DP, Davidsen JR, Rasmussen F.; Lancet Respir Med. 2014 Aug;2(8):638-46.
BACKGROUND: When used with standard diagnostic testing, point-of-care ultrasonography might improve the proportion of patients admitted with respiratory symptoms who are correctly diagnosed 4 h after admission to the emergency department. We therefore assessed point-of-care ultrasonography of the heart, lungs, and deep veins in addition to the usual initial diagnostic testing in this patient population.
2014 Aug - Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials
Calfee CS, Delucchi K, Parsons PE, Thompson BT, Ware LB, Matthay MA; NHLBI ARDS Network.; Lancet Respir Med. 2014 Aug;2(8):611-20.
BACKGROUND: Subphenotypes have been identified within heterogeneous diseases such as asthma and breast cancer, with important therapeutic implications. We assessed whether subphenotypes exist within acute respiratory distress syndrome (ARDS), another heterogeneous disorder.
David F. Gaieski, J. Matthew Edwards, Michael J. Kallan, Mark E. Mikkelsen, Munish Goyal, and Brendan G. Carr Am. J. Resp. Crit. Care Med. Sep 15, 2014, vol. 190, no. 6: 665-674
Rationale: Severe sepsis is increasing in incidence and has a high rate of inpatient mortality. Hospitals that treat a larger number of patients with severe sepsis may offer a survival advantage.
2014 Sep 15 - A Functional Synonymous Coding Variant in the IL1RN Gene Is Associated with Survival in Septic Shock
Nuala J. Meyer, Jane F. Ferguson, Rui Feng, Fan Wang, Parth N. Patel, Mingyao Li, Chenyi Xue, Liming Qu, Yichuan Liu, John H. Boyd, James A. Russell, Jason D. Christie, Keith R. Walley, and Muredach P. Reilly Am. J. Resp. Crit. Care Med. Sep 15, 2014, vol. 190, no. 6: 656-664
Rationale: Death from infection is a highly heritable trait, yet there are few genetic variants with known mechanism influencing survival during septic shock.
2014 Sep 15 - Multicenter Development and Validation of a Risk Stratification Tool for Ward Patients
Matthew M. Churpek, Trevor C. Yuen, Christopher Winslow, Ari A. Robicsek, David O. Meltzer, Robert D. Gibbons, and Dana P. Edelson Am. J. Resp. Crit. Care Med. Sep 15, 2014, vol. 190, no. 6: 649-655
Rationale: Most ward risk scores were created using subjective opinion in individual hospitals and only use vital signs.
The Hong Kong Society of Critical Care Medicine (香港危重病學會)will be holding its Annual Scientific Meeting (ASM) 2014(週年學術會議2014)on 30 November, 2014 (Sunday) at the Intercontinental Grand Stanford Hong Kong. And it is our pleasure to have the meeting supported by the Hong Kong Association of Critical Care Nurses (香港危重病學護士協會).
This is a major event for all Hong Kong doctors, nurses and allied health professionals working with critically ill patients. Similar to previous years, we will have renowned overseas and local speakers to enlighten us on important ICU topics in plenary lectures & seminars.
Continuing our tradition, SimWARS will be held and teams of doctors & nurses are invited to join this exciting competition. Young specialists and critical care nurses are encouraged to submit abstracts of original research papers for free-paper presentation, and share with the audience about their studies.
Details of the programme will be released soon. We sincerely hope to make the ASM an enjoyable and interesting event for all of you.
Looking forward to seeing you.
Dr. SIN, Kai Cheuk
Chairman of the Organizing Committee for HKSCCM ASM 2014
Date: 4 Sep 2014