Date: 27 May 2014; Time: 8:30 - 17:30
Venue: Accident and Emergency Training Centre of TSKH, 282 Queen's Road East, WanChai, Hong Kong
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Date: 11 Apr 2014; Time: 10:00; Activity; Visit by Department of Paediatrics and Adolescent Medicine, UCH on CIS applications in ICU
Date: 3-4 May 2014; Venue: Room N101, 1/F (New Wing), Hong Kong Convention and Exhibition Center
2014 Apr - Prediction of mortality in adult patients with severe acute lung failure receiving veno-venous extracorporeal membrane oxygenation: a prospective observational study
Tone Bull Enger, Alois Philipp, Vibeke Videm, Matthias Lubnow, Alexander Wahba, Marcus Fischer, Christof Schmid, Thomas Bein, Thomas Müller Critical Care 2014, 18:R67 (9 April 2014)
Introduction: Veno-venous extracorporeal membrane oxygenation (vvECMO) can be a life-saving therapy in patients with severe acute lung failure refractory to conventional therapy. Nevertheless, vvECMO is a procedure associated with high costs and resource utilization. The aim of this study was to assess published models for prediction of mortality following vvECMO and optimize an alternative model.
2014 Apr - Hemostasis during the early stages of trauma: comparison with disseminated intravascular coagulation
Akiko Oshiro, Yuichiro Yanagida, Satoshi Gando, Naomi Henzan, Isao Takahashi, Hiroshi Makise Critical Care 2014, 18:R61 (3 April 2014)
Introduction: We tested two hypotheses that disseminated intravascular coagulation (DIC) and acute coagulopathy of trauma-shock (ACOTS) in the early phase of trauma are similar disease entities and that the DIC score on admission can be used to predict the prognosis of patients with coagulopathy of trauma.
2014 Apr - Exploring the heterogeneity of effects of corticosteroids on acute respiratory distress syndrome: a systematic review and meta-analysis
Sheng-Yuan Ruan, Hsien-Ho Lin, Chun-Ta Huang, Ping-Hung Kuo, Huey-Dong Wu, Chong-Jen Yu Critical Care 2014, 18:R63 (7 April 2014)
Introduction: The effectiveness of corticosteroid therapy on the mortality of acute respiratory distress syndrome (ARDS) remains under debate. We aimed to explore the grounds for the inconsistent results in previous studies and update the evidence.
Date: 24 Apr 2014; Time: 6:30-9:30pm
Venue: Jordan Room, 2nd Floor, Eaton Hong Kong, 380 Nathan Road, Kowloon
CCM Board Accredited Tutorial
Marik PE.; Crit Care Med. 2014 Apr;42(4):962-9.
Background: Nutritional support is an essential component of the management of critically ill and injured ICU patients. Optimal provision of calories and protein has been demonstrated to reduce morbidity, mortally, and length of ICU and hospital stay. Yet, a large proportion of ICU patients receive inadequate nutrition.
2014 Apr - Liberal Versus Restricted Fluid Resuscitation Strategies in Trauma Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Observational Studies
Wang CH, Hsieh WH, Chou HC, Huang YS, Shen JH, Yeo YH, Chang HE, Chen SC, Lee CC.; Crit Care Med. 2014 Apr;42(4):954-61.
Objective: Hemorrhage is responsible for most deaths that occur during the first few hours after trauma. Animal models of trauma have shown that restricting fluid administration can reduce the risk of death; however, studies in patients are difficult to conduct due to logistical and ethical problems. To maximize the value of the existing evidence, we performed a meta-analysis to compare liberal versus restricted fluid resuscitation strategies in trauma patients.
Modem V, Thompson M, Gollhofer D, Dhar AV, Quigley R.; Crit Care Med. 2014 Apr;42(4):943-53.
Objectives: Acute kidney injury and fluid overload frequently necessitate initiation of continuous renal replacement therapy in critically ill patients admitted to the ICU. In this study, our primary objective was to determine the effect of timing of initiation of continuous renal replacement therapy on ICU mortality in children requiring renal support for management of acute kidney injury and/or fluid overload.
2014 Apr - A Feasibility Study of Cerebral Oximetry During In-Hospital Mechanical and Manual Cardiopulmonary Resuscitation
Parnia S, Nasir A, Ahn A, Malik H, Yang J, Zhu J, Dorazi F, Richman P.; Crit Care Med. 2014 Apr;42(4):930-3.
Objective: A major hurdle limiting the ability to improve the quality of resuscitation has been the lack of a noninvasive real-time detection system capable of monitoring the quality of cerebral and other organ perfusion, as well as oxygen delivery during cardiopulmonary resuscitation. Here, we report on a novel system of cerebral perfusion targeted resuscitation.
2014 Apr - Physical Complications in Acute Lung Injury Survivors: A Two-Year Longitudinal Prospective Study
Fan E, Dowdy DW, Colantuoni E, Mendez-Tellez PA, Sevransky JE, Shanholtz C, Himmelfarb CR, Desai SV, Ciesla N, Herridge MS, Pronovost PJ, Needham DM.; Crit Care Med. 2014 Apr;42(4):849-59.
Objective: Survivors of severe critical illness frequently develop substantial and persistent physical complications, including muscle weakness, impaired physical function, and decreased health-related quality of life. Our objective was to determine the longitudinal epidemiology of muscle weakness, physical function, and health-related quality of life and their associations with critical illness and ICU exposures.
2014 Apr - Do Physicians Have Lower Risk of Severe Sepsis and Associated Mortality? A Matched Cohort Study
Shen HN, Lu CL, Li CY.; Crit Care Med. 2014 Apr;42(4):816-23.
Objectives: Physicians generally have higher disease awareness and easier access to medical care, which may help them reduce risk of developing severe sepsis and associated mortality when they suffer from acute infection. However, the opposite situation may occur due to the presence of potential barriers to healthcare in physicians. We aim to examine the risk of severe sepsis and associated mortality in physicians.
2014 Apr - Troponin Elevation in Severe Sepsis and Septic Shock: The Role of Left Ventricular Diastolic Dysfunction and Right Ventricular Dilatation
Landesberg G, Jaffe AS, Gilon D, Levin PD, Goodman S, Abu-Baih A, Beeri R, Weissman C, Sprung CL, Landesberg A.; Crit Care Med. 2014 Apr;42(4):790-800.
Objective: Serum troponin concentrations predict mortality in almost every clinical setting they have been examined, including sepsis. However, the causes for troponin elevations in sepsis are poorly understood. We hypothesized that detailed investigation of myocardial dysfunction by echocardiography can provide insight into the possible causes of troponin elevation and its association with mortality in sepsis.
2014 Apr - Cost-Effectiveness of Histamine Receptor-2 Antagonist Versus Proton Pump Inhibitor for Stress Ulcer Prophylaxis in Critically Ill Patients
Maclaren R, Campbell J.; Crit Care Med. 2014 Apr;42(4):809-15.
Objective: To examine the cost-effectiveness of using histamine receptor-2 antagonist or proton pump inhibitor for stress ulcer prophylaxis.
2014 Apr - ABO Blood Type A Is Associated With Increased Risk of ARDS in Whites Following Both Major Trauma and Severe Sepsis
John P. Reilly, MD; Nuala J. Meyer, MD, FCCP; Michael G. S. Shashaty, MD; Rui Feng, PhD; Paul N. Lanken, MD, FCCP; Robert Gallop, PhD; Sandra Kaplan, BSN; Maximilian Herlim; Nathaniel L. Oz, BS; Isabel Hiciano, BA; Ana Campbell, MD; Daniel N. Holena, MD; Muredach P. Reilly, MBBCh; Jason D. Christie, MD CHEST Apr 2014; 145(4): 753-761
Background: ABO glycosyltransferases catalyze antigen modifications on various glycans and glycoproteins and determine the ABO blood types. Blood type A has been associated with increased risk of vascular diseases and differential circulating levels of proteins related to inflammation and endothelial function. The objective of this study was to determine the association of ABO blood types with ARDS risk in patients with major trauma and severe sepsis.
2014 Apr - Leveraging a Critical Care Database: Selective Serotonin Reuptake Inhibitor Use Prior to ICU Admission Is Associated With Increased Hospital Mortality
Marzyeh Ghassemi, MS; John Marshall, PharmD; Nakul Singh, MS; David J. Stone, MD; Leo Anthony Celi, MD, MPH CHEST Apr 2014; 145(4): 745-752
Background: Observational studies have found an increased risk of adverse effects such as hemorrhage, stroke, and increased mortality in patients taking selective serotonin reuptake inhibitors (SSRIs). The impact of prior use of these medications on outcomes in critically ill patients has not been previously examined. We performed a retrospective study to determine if preadmission use of SSRIs or serotonin norepinephrine reuptake inhibitors (SNRIs) is associated with mortality differences in patients admitted to the ICU.